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t r e a t e d

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d e p r e s s i o n

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d o c t o r .

Y o u r o p t i o n s m

a y i n c l u d e a d d i n g A B I L I F Y

/

t o t h e a n t i d e p r e s s a n t y o u ’ r e a l r e a d y t a k i n g .

ABILIFY is the only medicine FDA-approved to treat depression in adults when added

/

to an antidepressant (such as Lexapro® Zoloft,® Prozac® Effexor XRJ

or Paxil CR®).*

IM P O R TA N T S A FE T Y IN FO R M A TIO N :

Elderly patients with dementia-related psychosis (eg, an inability to perform daily activities

due to increased memoir loss) taking ABILIFY have an increased risk of death or stroke. ABILIFY

is not approved for treating these patients.

Antidepressants can increase suicidal thoughts and behaviors in children, teens, and young adults.

Serious mental illnesses are themselves associated with an increase in the risk of suicide.

When taking ABILIFY call your doctor right away if you have new or worsening depression

symptoms, unusual changes in behavior, or thoughts of suicide. Patients and their caregivers

should be especially observant within the first few months of treatment or after a change in

dose. Approved only for adults 18 and over with depression.

• Alert your doctor if you develop very high fever, rigid muscles, shaking, confusion, sweating, or

increased heart rate and blood pressure, as these may be signs of a rare but potentially fatal

condition called neuroleptic malignant syndrome (NMS)

• If you develop abnormal or uncontrollable facial movements, notify your doctor, as these may be

signs of tardive dyskinesia (TD), which could become permanent

• If you have diabetes or have risk factors or symptoms of diabetes, your blood sugar should be

monitored. High blood sugar has been reported with ABILIFY and medicines like it. In some cases,

extreme high blood sugar can lead to coma or death

• Other risks may include lightheadedness upon standing, seizures, trouble swallowing, or impairment

in judgment or motor skills. Until you know how ABILIFY affects you, you should not drive or operate

machinery

The common side effects in adults in clinical trials (>

%) include nausea, vomiting, constipation,

headache, dizziness, an inner sense of restlessness or need to move (akathisia), anxiety, and insomnia.

Tell your doctor about all the medicines you’re taking, since there are some risks for drug interactions.

You should avoid alcohol while taking ABILIFY.

IF A N A N T ID E P R E S S A N T

A LO N E ISN 'T EN O U G H .

A B I L I F Y

(aripiprazole)

2 mg, 5 mg Tablet

www.abilify.com

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call

-

-FDA-

.

Please read the Important Information about ABILIFY on the adjacent page.

*

Lexapro® (escitalopram oxalate), Zoloft® (sertraline HCI), Prozac® (fluoxetine hydrochloride), Effexor XR® (venlafaxine HCI), Paxil CR® (paroxetine HCI) are trademarks of their

respective companies.

:

Bristol-Myers Squibb

^ O t s u k c i oisuka Ametica Phamwceutkaiinc.

©2008 Otsuka America Pharmaceutical, Inc., Rockville. MD

570US08AB35606

December 2008

0308A-1776

Printed in USA